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Lymphocyte proliferation in glutathione-depleted lymphocytes: direct relationship between glutathione availability and the proliferative response

The active form of these proteins exists in a transient GTP bound state that mediates downstream signalling events

For this study, 5-week-old male C57BL/6N mice were used and maintained in a controlled setting with a temperature of (21 2) C, humidity between 45-55%, and a 12-hour light/dark cycle