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Dipeptide transporters such as PEPT2 also contribute to TMT by shuttling di- and tripeptides across the BBB [40,41,42]

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Under these pathological conditions, mitochondria play a pivotal role in regulating energy production and determining cell survival or death

A 2018 systematic review and meta-analysis identified 20 randomized controlled trials (published between 2007 and 2017) that examined the effect of supplemental lipoic acid on markers of glucose utilization in 1,245 subjects with metabolic disorders (not limited to type 2 diabetes) (60)