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A later case report demonstrated achievement of remission in a patient with extensive GVHD with DLI doses of 1 x 10 6 and 5 x 10 6 CD3+ cells/kg ( 8 cells/kg ( 7 cells/kg are sufficient to induce response with an acceptable rate of GVHD, while higher doses do not meaningfully increase response rates but do drastically increase the risk of toxicity ( 7 cells/kg with an interval of approximately four weeks between infusions to allow for development of GVHD, per EMBT guidelines ( 5 or 1 x 10 6 cells/kg may be considered

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Aging Albany NY 12:1686716886 Gu M, Cooper JM, Butler P, Walker AP, Mistry PK, Dooley JS et al (2000) Oxidative-phosphorylation defects in liver of patients with wilsons disease