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A study on the effects of long-term treatment with CoQ 10 (200 mg/day) plus selenium (200 g as selenized yeast) in a homogeneous Swedish healthy elderly population ( n = 219) revealed a significant reduction in cardiovascular mortality not only during the 4-year treatment period, but also 10 years later, compared to those taking either a placebo ( n = 222) or were without treatment ( n = 227) (Alehagen et al., Metabolic syndrome and diabetes CoQ 10 has been proposed for the treatment of metabolic syndrome and type 2 diabetes by virtue of its antioxidant properties

Lincoln DT, Ali EE, Tonissen KF, Clarke FM (2003) The thioredoxin-thioredoxin reductase system: over-expression in human cancer

However, it is worth noting that most clinical studies have analyzed the safety of glutathione up to 500 mg daily for up to two months

doi: 10.3389/fimmu.2024.1460286 Received 05 July 2024 Accepted 10 September 2024 Published 02 October 2024 Volume 15 - 2024 Edited by Yong Cao, Capital Medical University, China Reviewed by Ravi Manjithaya, Jawaharlal Nehru Centre for Advanced Scientific Research, India Heather M