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Many studies have investigated the protective effect of natural active ingredients against chemotherapy-related toxicity, revealing that they can effectively alleviate the damage of drugs to organs such as the kidney, heart, and intestine by regulating oxidative stress, inflammatory response, and key signaling pathways

These same principles, in view of the greater need for protein intake, can be attributed to canine and feline cancer patients, as they suffer from cachexia and sarcopenia syndromes

Participants were recruited from research centers located in Salvador, Bahia, Valinhos, and Bernardo do Campo, So Paulo, Brazil

2 Among these, cold exposure and fasting are well-studied paradigms that necessitate metabolic flexibility, prioritizing fatty acid oxidation over glucose catabolism to sustain systemic energy balance while sparing glucose for obligate tissues such as the brain