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The Tomas in vivo characterization in protein-restricted rats reported that IGF-I analogs that bind IGFBPs poorly including LR3-IGF-1 produce greater anabolic effects than equimolar native IGF-1 when administered by either continuous infusion or daily injection, with the differential most pronounced under injection conditions [2]

The SA/CoI/SDF-1 scaffold could maintain a milieu with biological compatibility and degradability for BMSCs to survive, migrate, and differentiate in vitro , while also being able to steadily release SDF-1 (Guo et al., 2020

Bromelain in burn care: advancements in enzymatic debridement and patient outcomes

The leap people make here is: if BPC-157 helps inflammatory bowel disease and ulcers in rats, maybe it helps IBS or leaky gut in humans