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TB-500 (Thymosin Beta-4) Research Wound Healing, Angiogenesis & Keratinocyte Migration (PubMed, 1999) A foundational pre-clinical study published on PubMed investigated Thymosin Beta-4 (TB4) in a rat full-thickness wound model

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they found that the c-MET inhibitor tivantinib reduces the synthesis of GSK3 by inhibiting MET activation, thereby stabilizing the expression of PD-L1 and blocking T cell-mediated cytotoxicity [139]