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For exercise performance and VO2 max improvement, the evidence from human exercise studies suggests that MOTS-c's acute rise following high-intensity training is part of the adaptive signal driving mitochondrial biogenesis and cardiovascular remodeling

Ito T., Sakakibara R., Ito S., et al., Mechanism of Constipation in Familial Amyloid Polyneuropathy: A Case Report, Internal Medicine 45, no