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5A-G Neurotransmitter patterns for Nle1-AngIV and Dihexa stimulated neurons

Persisters are frequently shielded from drug-induced oxidative stress and apoptosis-like pathways by molecular chaperones (most notably Hsp90 and small heat-shock proteins), the calcineurin signaling pathway, and enhanced antioxidant defenses (superoxide dismutases and other ROS-detoxifying enzymes) (OMeara et al., 2017

391,392,393 For example, coexisting Syn pathology in AD correlates with lower CSF P-tau181 and NG levels, 394 while comorbidity like hypertension lowers plasma A concentration but increases plasma P-tau181 and P-tau217 levels

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