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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

A more than fourfold increase in perifollicular vessel size was observed during the late anagen growth phase of the adult hair cycle, as compared with early anagen (Figure 1a), followed by complete reduction to pre-anagen sizes during the catagen and telogen phases (Figure 1, b and f)

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