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Why this trial matters: First bispecific + CD38 combo to show superior PFS and OS in Phase III in RRMM Potential new standard of care as early as second-line Demonstrates deep responses, high MRD-negativity, and durable outcomes First-line Strategies in BRAF V600E-Mutant mCRC: Real-World Evidence Signals Treatment Priorities In a real-world retrospective cohort of patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC), frontline chemotherapy plus anti-VEGF therapy was associated with the longest survival outcomes, while BRAF-targeted strategies showed promising response rates, emphasizing the need for tailored therapy and prospective validation

Current research on DNA methylation in OA primarily focuses on articular cartilage, the main tissue affected during disease progression and readily accessible from joint replacement surgeries

Syringe Units = Desired Dose (mg)Concentration (mg/mL) 100 Example: a 0.5 mg dose at 5 mg/mL = (0.5 5) 100 = 10 units