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Notably, the Firmicutes (85.3%) and Proteobacteria (4.9%) were also the predominated community in the T4 group, showing a higher microbial abundance compared to the T1 ( Firmicutes : 84.90%, Proteobacteria : 3.80%)

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SLU-PP-332 gained significant research attention following a 2023 publication in the Journal of Medicinal Chemistry (Ping et al., Washington University) demonstrating that the compound increased running endurance in mice by approximately 70% without training, alongside upregulation of mitochondrial biogenesis markers (PGC-1, TFAM) and oxidative fiber gene expression in skeletal muscle

Orally delivered NAC undergoes extensive first-pass metabolism resulting in about 90% loss by enzymic deacylation to form cysteine in the small intestine [9]