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The decline of NAD + with age results from three converging factors: (1) increased activity of CD38, a NADase whose expression increases with age-related chronic inflammation (inflammaging), (2) reduced biosynthesis via the NAMPT (nicotinamide phosphoribosyltransferase) and NMN pathways, and (3) increased demand for NAD+ by PARP-1 to repair increasing oxidative DNA damage

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Your provider may recommend high-dose B12 supplements or injections if you are [*]: Deficient based on bloodwork Following a plant-based diet Experiencing GI disorders like Crohns or celiac disease Recovering from bariatric surgery Do Prenatal Vitamins Have B12

Our Physician Medical Weight Loss Training course is CME-accredited and covers GLP-1 protocols, lipotropic and B12 injection technique and dosing, patient selection, comorbidity screening, and the program design that makes any of it work