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Polyphenols like resveratrol can alter drug metabolism in ways that are just as clinically significant as prescription drug-drug interactions.", This perspective reflects the standard pharmacovigilance position articulated in the Natural Medicines clinical monograph on resveratrol [5]

Other secondary causes of cognitive impairment, including genetic disorders (e.g., Wilsons disease), autoimmune conditions (e.g., SLE), chronic epileptic syndromes, repetitive head trauma (e.g., chronic traumatic encephalopathy) [501], and neoplastic processes or their treatments (e.g., chemotherapy-related cognitive impairment or brain fog) [502], are similarly well defined

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