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doi: 10.1016/j.rsma.2022.102278 49 HauxC.Larsson

Malhotra S, Sawhney G, Pandhi P

Clinical studies have confirmed a positive correlation between Nav1.7 channel density in skin nerve biopsies and pain scores in DPN patients (Lam et al., 2018)

Oxidative stress models subject mice to cigarette smoke, elevating ROS levels, diminishing the activity of the anti-apoptotic protein Bcl-2, and promoting caspase-3 cleavage