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The receptors for CGRP, specifically CLR and RAMP1, are expressed on macrophages, osteoblasts, and endothelial cells within bone tissue

It has gained significant interest for its regenerative properties and potential benefits in medical research purposes

[14] In a study conducted on football players at United States Military Academy, researchers found that the most common mechanism of injury is, "the compression of the fixed brachial plexus between the shoulder pad and the superior medial scapula when the pad is pushed into the area of Erb's point, where the brachial plexus is most superficial." [15] The result of this is a "burning" or "stinging" pain that radiates from the region of the neck to the fingertips