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Sci Rep 7, 2475 (2017) ( Licensed under CC-BY 4.0 ( Disclaimer Neither the license nor link to the foregoing publication constitutes or implies any sponsorship or affiliation with, or endorsement or approval of Renue By Science by the authors. RENUE - 2 Step Skin Rejuvenation Protocol RENUE SERUM IS QUICKLY ABSORBED Serums are made of very small molecules that penetrate your skin faster and more effectively, carrying the active ingredients to deeper layers and into systemic circulation. Step 1: Apply face or body serum for penetration to deepest skin layers and systemic circulation. Allow to soak in for 1-2 minutes RENUE LOTION PROTECTS SURFACE LAYER The thicker, more emollient ingredients in our Lotion and Face Creme concentrate more active ingredients in the surface layer. Step 2: Apply Renue Face Creme, Lotion, or your favorite moisturizer *note - Renue body lotion can be used alone, as the liposomes will also reach deep layers and systemic circulation, but in lesser quantities than serums It is more effective to apply the serum first, then the lotion. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease