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Similarly, the level of transthyretin in the BALF of patients with SSc-ILD was elevated, as detected by proteomic methods (44)

However, a small but statistically significant increase in micronucleus induction was observed in female p53 -haploinsufficient mice at 50 000 ppm (about 9620 mg/kg bw per day) (NTP, 2005)