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Description

Mechanistically, PGD2 released by monocytes and macrophages mediates the neuroprotective effect of HCA2 by resolving inflammation and inhibiting IB kinase (IKK) and NF-B, which are key players in ischemic brain damage

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An imbalance in relation of SOD to CAT and GPx results in the accumulation of H 2 O 2 , which may participate in the Fenton reaction, forming hydroxyl radicals