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Description

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Individuals with ASD exhibit dysregulated neuronal histone H3 lysine 4 (H3K4) methylation as well as upregulated histone deacetylase 4 (HDAC4) expression in the prefrontal cortex [92]

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ERRs bind to the promoter of PPARGC1A ( PGC-1 ) and transactivate it, and the resulting product then jointly activates ERRs

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