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Chen F, Castranova V, Shi X

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The PH domain of mSin1 is required for the insulin-dependent regulation of mTORC2 activity, which inhibits mTORC2 catalytic activity in the absence of insulin, and activates mTORC2 upon binding to PIP3 [77]

Lipton et al., 1991) undergoing fermentation by the gut microbiota at the colon level, thus inducing the observed modifications in the bacterial population.] Suez et al