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Polym Chem 1:16091614

PMID: [16814308] Rmi Longuespe Author profile: ORCID Rmi Longuespe is recognized for publications involving LC-MS/MS, MALDI imaging, peptide identification, and proteomic analytical methods

Two thiophenecarboxamide derivatives, compound 7,947,882 [5-methyl-N-(4-nitrophenyl)-thiophene-2-carboxamide] and 7,904,688 [3-phenyl- N -(4-piperidin-1-ylphenyl)-carbamothioyl-propanamide], which require activation by the monooxygenase EthA, may kill Mtb by inhibiting PyrG [295]

Therefore, they are more efficient in interacting with anionic siRNA molecules without significantly increasing the net charge of the LPNs