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Typically, for those with a significant deficiency, weekly injections may be recommended during the initial phase

If you choose to use a tuberculin syringe, convert your dose to milliliters first using this formula: mL = desired mg / concentration in mg/mL For 5 mg from a 10 mg/mL vial: 5 / 10 = 0.50 mL Then draw to 0.50 on the tuberculin syringe

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Similar to cagrilintide, pramlintide is primarily eliminated via the kidneys and, in a pharmacokinetic study in participants with type 1 diabetes, no statistically significant differences were noted in total (AUC 0- ) and peak ( C max ) exposure after administration of a single pramlintide 60 g dose in participants with mild, moderate or severe renal impairment compared with those with normal renal function, although inter-patient variability was high [20]