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The impacts of several risk factors and biomarkers, including as tau hyperphosphorylation and A elevation, may be caused by impaired neuroplasticity and mitochondrial dysfunction (97), which may be a common upstream etiology of AD

Proc Natl Acad Sci USA 118:e2020322118 Liebschner D, Afonine PV, Baker ML, Bunkczi G, Chen VB, Croll TI, Hintze B, Hung L-W, Jain S, McCoy AJ et al (2019) Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

a similar trend has been demonstrated for other OXPHOS complexes, including complex V [36]

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