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Since methylene blue can cross the blood-brain barrier (the protective layer that controls the passage of substances between the bloodstream and the brain), some researchers are studying whether it can help reduce oxidative stress on mitochondria and improve memory

doi:10.1080/10408398.2020.1823814

P2Y1R-initiated, IP3R-dependent stimulation of astrocyte mitochondrial metabolism reduces and partially reverses ischemic neuronal damage in mouse