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Because dihexa is investigational, its long-term safety in humans isn't fully established and that uncertainty is itself the reason for medical oversight

therefore, these reactions are termed 'idiosyncratic' DILI (IDILI).4 Many drugs have been identified to cause IDILI in humans.5 Antithyroid drugs-induced hepatic injury is categorized as IDILI.6 Due to its high morbidity and mortality, and unpredictable nature, DILI has become a major clinical challenge.7 Moreover, DILI accounts for a large number of drug withdrawals from the marketplace, or discontinuation of further development of a drug candidate

Locus of enterocyte effacement from Citrobacter rodentium : Sequence analysis and evidence for horizontal transfer among attaching and effacing pathogens

25, 38, 40 BSO+L-PAM was synergistic (CIN 0.30.7) in OPM-2 (t(4;14)(p16;q32)), NCI-H929 (t(4;14)) TX-MM-030h (post-BMT) and MOLP-2 (t(11;14)(q13;q32)) 39 cell lines (Figures 1ac)