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Multi-Modal approaches for neurological diseases Multi-modal strategies, which integrate therapeutic and diagnostic functions, are increasingly being developed to tackle the complexity of neurological diseases

While [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) studies have shown increased glucose uptake following severe TBI in humans (Bergsneider et al., 1997), no studies have examined this immediate increase in glucose uptake after mild or concussive brain injuries