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The protein abundances of all western blots per condition were measured by densitometry of the bands, in the linear phase of the exposure without reaching saturation, on the films or on the scanned autoradiograms using ImageJ v.1.48 software

Because activated CD8+ T-cells depend on sustained glycolysis, excess extracellular lactate disrupts lactate efflux, leading to intracellular acidification and metabolic dysfunction that blunt T-cell activity within the GBM TME