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Here we have elucidated the complex crosstalk between the TGF-- and HGF-dependent signaling pathways in gliobastoma using three patient-derived GIC models as well as human glioblastoma specimens

Cerebrolysin: A peptide mixture derived from porcine brain proteins and used medically in some countries for neurological conditions

However, direct agonist stimulation of dopaminergic receptors present on NSCs in the SVZ, to promote adult neurogenesis, may represent the most clinically promising approach for PD patients when taking into consideration the substantial loss of dopaminergic neurons at the time of disease diagnosis [113, 127]

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