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Overactivation of the RANK signaling pathway in Neu and MMTV-PyMT oncogenic mouse models delays breast cancer onset and promotes subsequent metastatic invasion (168)

The characteristics of the reviewed studies, including exposure levels, and main results are summarized in Tables 3 and 4

Embodiment 102 The antibody according to any one of embodiments 1-8, wherein said antibody comprises a heavy chain variable region (VH) of an M25ADL99G antibody and a light chain variable region (VL) of an M25ADL99G antibody