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Despite advancements in therapeutic approaches, the incidence and mortality associated with arrhythmia remain high, and drug-related adverse effects continue to pose significant challenges

Compounded medications have not been approved by the FDA and the FDA has not evaluated their safety or efficacy.

However, it is worth noting that iron accumulation at the hypothalamic-pituitary level may impair Gonadotropin-releasing hormone neurons and/or pituitary gonadotroph cells and lead to hypogonadotropic hypogonadism, which is characterized by low levels of gonadotropins (FSH and LH) and testosterone, thus indirectly affecting testicular function [67, 68]

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