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Copper metabolism requires precise regulation to maintain the homeostasis of this redox-active metal

The absorbance of the formed NADH was measured at 340 nm, which is directly proportionate to the cholesterol concentration in the sample

Abbreviations ART: Antiretroviral therapy PLWH: People living with HIV HAND: HIV-associated neurocognitive disorder CUD: Cocaine use disorder BBB: Blood brain barrier CNS: Central nervous system IRG1: Immune responsive gene 1 Acod1: Aconitate decarboxylase 1 4OI: 4-Octyl-itaconate Nqo1: NAD(P)H quinone oxidoreductase 1 Gstp1: Glutathione Stransferase Pi Gclc: Glutamate cysteine ligase catalytic subunit VASP: Vasodilator Stimulated Phosphoprotein References Aksenov MY, Aksenova MV, Nath A, Ray PD, Mactutus CF, Booze RM (2006) Cocaine-mediated enhancement of Tat toxicity in rat hippocampal cell cultures: the role of oxidative stress and D1 dopamine receptor

Conversely, the abundance of taxa associated with common diseases (e.g., Enterobacter and Staphylococcus ) was relatively increased