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Concurrently, antioxidant co-loading (e.g., vitamin E TPGS) synergistically enhances oxidative stability while acting as an emulsifier in PLGA nanoparticles, where its amphiphilic structure simultaneously inhibits peroxyl radical-mediated degradation and improves cellular uptake [87, 88]

Medullary Thyroid Carcinoma or MEN 2 , Patients with a personal or family history of medullary thyroid carcinoma, or those diagnosed with Multiple Endocrine Neoplasia syndrome type 2, should not use tirzepatide

[DOI] [PMC free article] [PubMed] [Google Scholar] 398.Andreani T., Fangueiro J.F., Severino P., de Souza A.L.R., Martins-Gomes C., Fernandes P.M.V., Calpena A.C., Gremio M.P., Souto E.B., Silva A.M

How can we optimize the bioavailability and stability of natural antioxidants to enhance their therapeutic efficacy in managing oxidative stress