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It is evident that disorders of glucose metabolism in the form of diabetes and IR are the core elements of the MetS

Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

For example, people who follow vegetarian or vegan diets may have a higher risk of B12 deficiency because the vitamin is not naturally present in plant-based foods