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In contrast, eumelanin is a highly diverse polymer made up of units such as 5,6-dihydroxyindole (DHI) and 5,6-dihydroxyindole-2-carboxylic acid (DHICA)

Among them, the best known ROS in human cells include superoxide anion (O 2 - ), which is the precursor of most other ROS, hydroxyl radical ( OH), peroxyl radical (ROO ), hydroperoxyl radical ( HO 2 ), and hydrogen peroxide (H 2 O 2 ), although the last one is not technically a free radical because it does not have unpaired electrons, but it represents a source of them [25] (Fig

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