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Cancers (Basel) 11:E345

Supporting clean-room or analytical laboratory protocols

Moreover, cystine starvation induces mitochondrial fragmentation and ROS production, leading to necroptosis and ferroptosis in BLBC cells via the tumor necrosis factor alpha (TNF) and MEKK4-p38-Noxa pathways, while luminal-type breast cancer, without activation of these pathways, is cystine independent 48,49