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The gene expression profiling results revealed that NAC treatment changed the expression of genes related to immune response, inflammatory response, oxidation-reduction processes, cytokine-cytokine receptor interactions, and cytokine-mediated signalling, Toll-like receptor signalling, Jak-STAT signalling, TNF signalling pathways

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Seventy-one hits were identified to bind at the substrate-binding site, and three hits were found to bind near the dimer interface