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A deficiency in this crucial vitamin can lead to a range of health issues, including anemia, fatigue, neurological problems, and cognitive difficulties

Vascular EDS (vEDS) is caused by pathogenic variants in COL3A1 , 3 which encodes the pro-1 chain of type III collagen (OMIM 130050) and occasionally specific COL1A1 variants may lead to a vEDS phenotype