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Moreover, a phenotypic study on human primary macrophages and stellate cells suggested that AXA1125 can inhibit lipopolysaccharide (LPS)-induced TNF- expression in M1 macrophages and increase the secretion of anti-inflammatory chemokine C-C motif ligands by M2 macrophages, as well as reduced Pro-C3 and HSP47 expression in HSC

Important Notes Practical framing points that keep the record honest and consistent with how the molecule was actually developed

There is limited evidence with doses higher than 4060mg/day

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