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Tirzepatide may be considered for its approved metabolic indications in these patients, but it should not replace or delay established autoimmune disease treatments

PMID: 40729432 PLoS Pathog2025 Oct 24;21(10):e1013615

12 , 15 CLINICAL EVIDENCE In the late 1960s, clinicians recognized that acute acetaminophen overdose caused a dose-related liver injury and that without treatment many patients die