glutathione synthetase deficiency smear Diagnosis from the Blood #imageoftheday, ๐ A 24-year-old man
#imageoftheday, A 24 year old man develops acute jaundice and dark urine after starting trimethoprim sulfamethoxazole. A peripheral smear reveals the specific cellular defects shown. The underlying Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation Scientific Reports Hematological Diagnostics Springer Nature Link Impaired Glutathione Synthesis in Neurodegeneration
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