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Symptoms of a vitamin B6 deficiency may include: Depression Confusion Microcytic anemia Poor Dream Recall Dermatitis with cheilosis Poor immune function MSG sensitivity Poor caffeine metabolism (coffee makes them jittery) Poor glucose tolerance Calcium oxalate kidney stones Nausea and water retention during pregnancy Abnormally acute hearing in infants Convulsive seizures in infants Irritability in infants Asthma Epilepsy Visual Disturbances Risk Factors for Vitamin B6 Deficiency Older individuals, people with renal problems, people with alcohol use disorder, and those with vitamin malabsorption issues are at a higher risk for developing vitamin B6 deficiency