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The toxins, enzymes and metabolites of bacteria (predominantly Gram-negative anaerobic) present in the dental plaque play a key role in the initiation of the inflammatory process, but the exact pathomechanism is far from being understood in detail (5-8)

MCE, HY-106376) and trolox (Sigma-Aldrich, 238813) were diluted in water at 100 mM and added at the indicated concentrations

Synthetic Production and Formulation Advances in peptide technology now allow GHK-Cu to be produced synthetically and included in a wide range of topical products, from serums and creams to more concentrated solutions

This makes it significantly more effective, even at lower doses, than standard forms