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Some drugs may be associated with a specific pattern of pigmentation

[11] [12] History and research [edit] Research in the early 1960s showed that in rats, administration of -MSH caused sexual arousal, and work on this continued in many labs up through the 1980s, when scientists at the University of Arizona began attempting to develop -MSH and analogs as potential sunless tanning agents, and synthesized and tested several analogs, including melanotan-I and melanotan II

doi: 10.1016/s1092-9134(03)00073-x 53 MandyburTI

PDE5 inhibitors, such as sildenafil and tadalafil, improve erectile function by inhibiting phosphodiesterase-5