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Gastroenterology 161 , 14751486 (2021)

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As a structural analog within the copper peptide class, it has been examined alongside GHK-Cu in preclinical models investigating copper-dependent enzymatic activity, extracellular matrix remodeling, and cellular signaling pathways relevant to skin and connective tissue biology

DNA was not isolated from the first two samples collected in the LD/LD-V group, and the first sample collected in each of the other respective groups, due to the use of saline to flush the cecum (after weighing) during early collection (therefore, n = 25 cecal samples)