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Constipation: Less common than diarrhea but still possible

The pharmacokinetic groundwork that is also missing Even before an efficacy trial, injectable GHK-Cu lacks the basic human pharmacokinetic characterization that any injectable drug candidate would require: measured plasma half-life of the intact complex, the fraction of administered copper that binds to plasma proteins versus remains peptide-bound, tissue distribution, and how much functional complex if any actually reaches the dermis

Pen, G., Yang, N., Teng, D., Mao, R., Hao, Y., and Wang, J., Antibiotics (Basel), 2020, vol