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Humans taking ME-3 for four weeks experienced a 16% reduction in oxidized LDL-cholesterol, a 20% decrease in 8-isoprostanes, which is a marker of free radical damage, a remarkable 49% increase in the ratio between reduced to oxidized glutathione, and a 26% increase in total antioxidant activity throughout the entire body

Front Pharmacol 11:413 Huguenard JR (1996) Low-threshold calcium currents in central nervous system neurons

The 5 % w/v TNBS was diluted in an equal volume of 100 % ethanol (working solution of 2.5 % TNBS in 50 % ethanol) and given to the rats at a dose of 100 mg/kg of body weight (Xu et al., 2017)

These rats were then administered CAPE therapy at 10 mg/kg via intraperitoneal injection, commencing 30 min after the injury