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Until these studies are conducted, a reasonable recommendation for physicians and their patients who are taking these drugs is to monitor vitamin B-12 status and to provide vitamin B-12 supplements if altered blood biomarkers or clinical signs consistent with low or deficient vitamin B-12 status develop

Vitamin B12 is needed to make new cells in the body, such as the many new red blood cells which are made every day

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But at higher doses like 5mg per week, that same vial lasts only two weeks, meaning nearly half the reconstituted solution never gets used before the 28-day limit if you are only at the start of your protocol