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Redox status in mammalian cells and stem cells during culture in vitro: Critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance

Indeed, this is readily observed in diseases such as thalassemia and sickle cell anemia

A different research team also indicated that erastin, sorafenib, and buthionine sulfonimine, which are ferroptosis inducers, augmented NRF2 expression in HCC cells [92]