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Semax (100 nM) can increase the survival rate of cholinergic neurons in the basal forebrain and stimulate the activity of choline acetyltransferase in cultured basal forebrain tissue ex vivo [2]

To address these challenges, it is essential to develop ligand scaffolds incorporating bioorthogonal conjugation sites, such as azides or alkynes appropriate for copper-free click chemistry, that are positioned away from the coordination sphere

Compare that to fighting traffic to a clinic, waiting, receiving treatment, and commuting back and the convenience argument becomes obvious

If you are oestrogen or progesterone deficient, you can correct this with 'natural progesterone' HRT, in the form of a transdermal skin cream